The Physiology and Pathophysiology of Vitamin D

Vitamin D Metabolism and Physiology

Background. Vitamin D insufficiency may lead to various health problems. By encouraging sun protection to prevent skin cancer, physicians may be limiting a major source of vitamin D for many individuals. Methods. We did a literature review on issues related to vitamin D inadequacy, particularly those relevant to various racial/ethnic groups. Results. Vitamin D is an important hormone with many ...

The physiology of vitamin D : current concepts.

The vitamin D endocrine system, besides playing pivotal roles in calcium homeostasis & bone mineral metabolism, is now recognized to subserve a wide range of fundamental biological functions in cell differentiation, inhibition of cell growth as well as immuno modulation. Vitamin D is a prohormone which is converted into its active hormonal form 1, 25 (OH)D2 D, 1, 25 (OH)D2 D activates its cellu...

The physiology and treatment of vitamin D deficiency.

Vitamin D across the lifecycle: physiology and biomarkers.

The field of vitamin D public health research has a pressing need to define sensitive and specific predictors of vitamin D status that can be used to determine whether an individual or population has a supply of vitamin D that is sufficient to meet requirements. The aim of this review is to highlight the considerations needed when evaluating evidence of the relations between vitamin D biomarker...

Vitamin D in the skin physiology and pathology.

Vitamin D plays important, pleiotropic role in the maintenance of global homeostasis. Its influence goes far beyond the regulation of calcium and phosphorus balance, as diverse activities of vitamin D and its natural metabolites assure proper functioning of major human organs, including skin. Recently, we reviewed the current understanding of vitamin D impact on human health from historical per...